In my opinion Deneghra 2 works better as a melee list. If you want to play a ranged list, I think it might be better to sub in Deneghra 1?
I've played Aiakos with Seethers with Deneghra 2 before and while the Seethers themselves do work (12" threat, need no focus to charge, don't take a focus burden from Denny and can get Grievous Wounds), it is very hard to keep Aiakos safe when baby sitting 2 melee jacks.
Deathjack is also very nice with her to get a second Hellmouth in, but he's a huge focus sink and isn't that much harder to kill than a regular Cryx jack (well he is, but most lists can handle him)
What kind of changes are you looking for, what do you have available?